Endocrine Abstracts

Background Comprehensive evaluation of the effect of surgery in patients with primary hyperparathyroidism (PHPT) and monitoring of patient’s well-being after treatment including assessment of patient-reported outcomes is worthwhile.AIMWe aimed to assess changes in quality of life (QoL) and symptoms in patients with symptomatic and asymptomatic PHPT after surgery (parathyroidectomy, PTX).Materials and methods.Adult patients wit...

Background: Hypoparathyroidism is one of the most important complications of total thyroidectomy. Its treatment with the use of recombinant parathyroid hormone (PTH) is limited now, therefore the prophylaxis of post-surgical hypoparathyroidism is very important. A method of tension-free thyroidectomy (TFT) was proposed in 2021. TFT uses unusual medial approach to the recurrent laryngeal nerves (RLN) and parathyroid glands (PG), together with several principles decreasing tract...

Background: SARS-CoV-2 profoundly impacts population health through both acute infection and post-COVID period. Multiple studies make it clear that metabolic diseases can significantly affect the course of COVID-19.Aim: To study the course of post-COVID period in patients with type 2 diabetes mellitus (DM2).Methods: The international registry ACTIV SARS-CoV-2 (NCT04492384) was established to study COVID-19 in the Eurasian region. T...

Background: The literature shows that body mass index (BMI) and blood glucose levels can significantly influence the course of infectious diseases. In the light of ongoing SARS-CoV-2 pandemic, its rational treatment and prevention are strategic public health goals.Aim: To study the relationship between BMI and serum glucose levels during the acute period of COVID-19 in hospitalized patients.«ACTIV SARS-CoV-2» registry was established to evaluat...

The diagnosis of subclinical hypercortisolemia in patients with incidental adrenal tumors remains a challenge, as there are no unambiguous criteria for diagnosis. The discovery of a substance whose secretion increases under the influence of cortisol would make it easier to make therapeutic decisions. Hypercortisolism causes a change in the distribution of adipose tissue, so it can be assumed that it also affects secretion of proteins secreted by adipocytes (adipokines). The ai...

Aim: The aim of the study was to investigate the clinical and hormonal effectiveness of different modes of suppressive cabergoline (CAB) therapy during 12 months in patients with prolactinoma.Subjects and methods: It was examined and underwent a 12 month course of treatment by selective dopamine agonist CAB in 61 patients with prolactinoma (PROL) (9 male/ 52 female) aged 16–66 years. There were 40 women with microPROL, 12 with macro&giant PROL; ...

Introduction: In everyday practice, doctors often have to deal with patients who show features of depression - it has been proven that in 20–30% of cases it may be related to the ocurrence of another disease, such as hypothyroidism.Aim of study: The aim of the study was to verify the frequency of occurrence features of depression (based on Beck’s scale) in the population of patients with hypothyroidism and comparison to the general population.<...

Objective: Among women over 40 the prevalence of goiter in Poland is over 40% and the prevalence of vitamin D deficiency is over 80%. There have not been any previous studies that investigate the vitamin D level in women with and without goiter.Methods: 152 women-96 with and 56 without nontoxic goiter were examined in 2014. In US examination we calculated the volume of the thyroid gland and volume of nodules. Blood samples for 25-(OH) D total were taken....

52 years old man medicated with amiodaron 12 months, with laboratory confirmed hyperthyroidism, in us-examination 45 ml Basedow goiter, TRAb positive; ventricular tachycardia 180/min intermittent with sinusal tachycardia 120/min, thiamasol 120 mg i.v./daily, hydrocortisone 400 i.v. daily, crystalloids, beta blockers, diazepam, albumin. J131 scintigraphy – no iodine uptake. natriumperchlorate 1500 mg daily initially, continued next month 900 mg coused iodine uptake 17%. Fi...

Purpose: To investigate the kinetics of adrenocorticotropin (ACTH) following oral metyrapone administration and describe differences between ACTH-deficient and non ACTH-deficient subjects.Methods: Patients from a tertiary endocrine center at a University Hospital in Munich, Germany, were tested. Metyrapone (Metopirone, HRA Pharma, France) was administered with a dosage of 40 mg/kg bodyweight at 0800 h. Consecutive levels of ACTH were determined at 0, 60,...